neuromuscular junction disease การใช้

Acquired myasthenia gravis is the most common neuromuscular junction disease . ( reference 7 ) Important observations were made by Patrick and Lindstrom in 1973 when they found that antibodies attacking the acetylcholine receptors were present in around 85 % of cases of myasthenia gravis . ( reference renamed form 13 ) ( reference 36 ) The remaining diseases were also a result of antibody attacks on vital proteins, but instead of the acetylcholine receptor, the culprits were MuSK, a muscle-specific serum kinase, and lipoprotein receptor-related protein . ( reference 36 ) So these mechanisms describe myasthenia gravis that is acquired, and not congenital, affecting these vital proteins by an immunological response against self-antigens.